Process for reducing reflex tachycardia in the treatment of hype

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514401, A61K 31415, A61K 31495

Patent

active

047466600

ABSTRACT:
The invention relates to a new process for the treatment of hypertension and thromboembolic diseases in humans by simultaneous administration of (.+-.)- or (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene hydrochloride on the one side, and 4,5-dihydro-6-[4-(1-imidazolyl)-phenyl]-5-methyl-3(2H)-pyridazinone or 4,5-dihydro-6-[4-(1-imidazolyl)-thien-2-yl]-5-methyl-3(2H)-pyridazinone, on the other side, as the active substances.

REFERENCES:
patent: 4518783 (1985-05-01), Biedermann et al.
patent: 4643998 (1987-02-01), Hilboll et al.
Derwent Publication 67658x/36 of German Patent 1,795,843, 1 page (1968).

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