Process for reducing nucleic acid content of yeasts and bacteria

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195 28N, 195 82, 195 96, 426 62, C12C 1100

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active

039680096

ABSTRACT:
Process for reducing nucleic acid content of yeasts and bacteria comprising heat shocking for a period of time and at a temperature selected to increase effectiveness of enzymes which break down nucleic acids without allowing proteins to break down or leak out of the cell, and incubating the heat-shocked cells at a temperature lower than the heat shock temperature under conditions in which the cells remain intact and nucleic acid fragments permeate the cell walls.

REFERENCES:
patent: 3139385 (1964-06-01), Ogata et al.
patent: 3720585 (1973-03-01), Tannenbaum et al.
Haight et al., J. of Bacteriology vol. 92 No. 2 pp. 1388-1393, Nov. 1966.

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