Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Solid support and method of culturing cells on said solid...
Reexamination Certificate
2004-11-26
2011-12-20
Tate, Chris R (Department: 1657)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Solid support and method of culturing cells on said solid...
C435S004000, C435S041000, C435S243000, C435S253600, C435S289100, C435S395000
Reexamination Certificate
active
08080419
ABSTRACT:
This invention relates to methods for use in industrial production of proteins. Specifically, the present invention provides a method of recycling solid supports for cultivation of anchorage-dependent cells such as, e.g., microcarriers and Fibra-Cel® disks. Solid supports recycled by a method of the present invention allow obtaining a protein productivity level comparable to the productivity level obtained with non-recycled solid support. The method comprises the steps of rinsing with water, rinsing with a sodium hydroxide solution and second rinsing step with water.
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Bernard Alain
Papp Frederic
Ares Trading S.A.
Kosar Aaron J
Saliwanchik Lloyd & Eisenschenk
Tate Chris R
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