Process for recovering macromomycin

Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Processes of making – purifying or recovering

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A61K 3500

Patent

active

041645677

ABSTRACT:
There is provided a process for recovering macromomycin (hereinafter referred to as MCR) which comprises adding coagulants or coagulants and neutralizers to a culture filtrate saturated with ammonium sulfate and collecting the resulting precipitate containing MCR in a high yield at low centrifugal force. From the precipitate obtained, MCR powders can be prepared according to the methods described in U.S. Pat. No. 3,595,954 and others.

REFERENCES:
patent: 3505449 (1970-04-01), Harned
patent: 3595954 (1971-07-01), Umezawa et al.

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