Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1995-03-03
2000-02-29
Woodward, Michael P.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530380, 530413, 530427, 514 21, C07K 14745
Patent
active
060310812
ABSTRACT:
A process is described for reactivating purified membrane proteins in which a mixture composed of membrane protein, a phospholipid and a detergent is frozen and subsequently thawed.
REFERENCES:
patent: 5426031 (1995-06-01), Hawkins et al.
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Guha et al., "Affinity Purification of Human Tissue Factor: Interaction in Detergent Micelles" P.N.A.S. v. 83, pp. 299-302, 1986.
Brotherus et al., "Soluble and Enzymatically Stable (Sodium, Potassium)--ATPase from Mammalian Kidney Consisting Predominantly of Protomer .alpha..beta.-units: Preparation, Assay and Reconstitution of Active Sodium, Potassium Transport," Biological Abstracts 76(10):7890, Abstract 71791 (1983).
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Sasaki et al., "Molecular Mechanism of Regulation of Ca.sup.2+ Pump ATPase by Phospholamban in Cardiac Sarcoplasmic Reticulum," Journal of Biological Chemistry 267(3):1674-79 (1992).
Contino et al., "Use of an Oriented Transmembrane Protein to Probe the Assembly of a Supported Phospholipid Bilayer," Chemical Abstracts 121(19):566, Abstract 225786c (1994).
Jones et al., "Solubilization & Reconstitution of Membrane Proteins", Biosis #87:494121 (1987) Whole Document.
Dade Behring Marburg GmbH
Woodward Michael P.
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