Process for reacting fluorine-substituted heterocycles with amin

Details Process for reacting fluorine-substituted heterocycles with amin Process for reacting fluorine-substituted heterocycles with amin

1998-10-14

2000-06-27

McKane, Joseph K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544208, C07D26536, C07D25118

Patent

active

060808586

ABSTRACT:
Process for reacting fluorine-substituted heterocycles with amines in the presence of phase transfer catalysts The reaction of an amino compound with a fluorine-substituted triazine or pyrimidine group is carried out in the presence of a phase transfer catalyst, preferably of the formula (4a), (4b) or (4c) ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are identical or different and are each alkyl having from 1 to 20 carbon atoms which may be substituted by phenyl, or are phenyl.

REFERENCES:
patent: 4189570 (1980-02-01), Bonometti et al.
patent: 4189576 (1980-02-01), Altorfer et al.
patent: 5440039 (1995-08-01), Frosch et al.

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