Process for racemization of optically active 1-phenylethylamine

Details Process for racemization of optically active 1-phenylethylamine Process for racemization of optically active 1-phenylethylamine

1996-12-05

1998-03-03

Burn, Brian M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564271, C07C20900

Patent

active

057236720

ABSTRACT:
A process for racemization of an optically active 1-phenylethylamine derivative represented by formula (I): ##STR1## wherein R.sup.1 represents a phenyl group substituted at least at the ortho-position, which comprises reacting the optically active 1-phenylethylamine derivative (1) with an aldehyde compound represented by formula (2):

REFERENCES:
patent: 4252744 (1981-02-01), Bison et al.
patent: 5504253 (1996-04-01), Van Wagenen et al.
Patent Abstracts of Japan, Publication No. 08027073 (EPO) (1996).
Patent Abstracts of Japan, Publication No. 07188120 (EPO) (1993).
Hashimoto et al. (1995) Tetrahedron letters, vol. 36, No. 48, pp. 8821-8824 .

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