Process for quantifying glycosaminoglycans in antithrombin III-c

Details Process for quantifying glycosaminoglycans in antithrombin III-c Process for quantifying glycosaminoglycans in antithrombin III-c

1997-08-13

2000-09-12

Housel, James C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving blood clotting factor

435 792, 435 13, 435 696, 435962, 436 69, 436177, 436178, 436825, 530380, 530381, 530382, 530383, 530384, G01N 3353, G01N 118, C12Q 156, C12P 2106

Patent

active

061176478

ABSTRACT:
A process for determining glycosaminoglycans in antithrombin III (ATIII)-containing solutions by increasing the ionic strength of the AT III-containing solution until the interaction between AT III and glycosaminoglycans is prevented, removing the AT III which has been released from the glycosaminoglycans from the solution, and desalting and determining the glycosaminoglycan which has remained in the solution.

REFERENCES:
patent: 5304638 (1994-04-01), Marshall et al.
patent: 5320945 (1994-06-01), Dessauer et al.
Gressner et al. J. Clin. Chem. & Clin. Biochem. vol. 21; pp. 407-416, 1983.

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