Process for purifying vinylically unsaturated compounds prepared

Organic compounds -- part of the class 532-570 series – Organic compounds – Silicon containing

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585435, 585638, 585641, 585642, 560205, 556450, 556453, 210656, 203 99, C07F 708

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054912504

ABSTRACT:
A crude vinylically unsaturated product formed from a palladium-complex-catalyzed reaction of a reactant halide selected from the group consisting of aryl, allyl, vinyl, and benzyl halides, and a reactant olefin having a vinylic hydrogen, wherein the reaction is carried out in the presence of a hydrogen halide acceptor, is purified by first contacting the crude product with a base that is stronger than the hydrogen halide acceptor, then heating the stronger base-contacted product. The purified product shows a marked reduction in concentration bromine and palladium impurities. The product can then be further purified by such methods as chromatography, crystallization, or distillation to achieve a product that is more suitable for applications where very low levels of inorganic impurities are required.

REFERENCES:
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patent: 4658071 (1987-04-01), Seufert et al.
patent: 4822930 (1989-04-01), Liu
patent: 5138081 (1992-08-01), DeVries et al.
patent: 5243068 (1993-09-01), DeVries et al.
patent: 5264646 (1993-11-01), DeVries et al.
patent: 5424470 (1995-06-01), Bank et al.
Heck, Richard F., Palladium-Catalyzed Vinylation of Organic Halides, Organic Reactions, vol. 27, pp. 345-390 (1982).

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