Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1995-05-25
1996-12-10
Housel, James C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
4242691, 530350, 530412, 5303881, A23J 100, A61K 39002, C07K 100, C07K 1600
Patent
active
055832040
ABSTRACT:
An assay to confirm the presence of antibodies to T. cruzi in a test sample. The assay comprises detecting the presence of antibody to three T. cruzi antigens, Gp 90, Gp 60/50 and LPPG in a test sample. The presence of antibody in the test sample to at least two of three T. cruzi antibodies is indicative of a confirmed reactive sample. Also provided are diagnostic reagents for detection of T. cruz, a process for purifying GP 60/50, a process for linking a protein and LPPG, and diagnostic test kits for use when assaying for antibodies to T. cruzi.
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Pan Alfred A.
Winkler Martin A.
Abbott Laboratories
Becker Cheryl L.
Housel James C.
Porembski Priscilla E.
Shaver Jennifer
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