Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1987-10-26
1991-04-30
Draper, Garnett D.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
530412, 530418, 530419, 530422, 530300, 530350, 530824, 530371, 424 89, C07K 326
Patent
active
050119150
ABSTRACT:
Methods of purifying recombinant surface antigen of hepatitis B virus are disclosed. In one protocol, purification is achieved by selective extraction of the antigen from yeast membranes, followed by solubilization with urea and dithiothreitol.
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Caruso Charles M.
Draper Garnett D.
Merck & Co. , Inc.
Meredith Roy D.
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