Process for purifying proteins and compounds useful in such proc

Details Process for purifying proteins and compounds useful in such proc Process for purifying proteins and compounds useful in such proc

1984-12-05

1986-02-11

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112R, 2601125R, 2601125LH, 2601125S, 2601125E, 2601127, 260114, 260115, 260121, C07G 704

Patent

active

045697949

ABSTRACT:
This invention describes a process for separating a biologically active polypeptide or protein in the form of its precursor from a mixture containing said precursor and impurities, which comprises contacting said precursor with a resin containing immobilized metal ions, said precursor comprising the biologically active polypeptide or protein covalently linked directly or indirectly to an immobilized metal ion chelating peptide, binding said precursor to said resin, and selectively eluting said precursor from said resin. Such precursor compounds are also described.

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