Process for purifying proinsulin-like materials

Details Process for purifying proinsulin-like materials Process for purifying proinsulin-like materials

1985-04-08

1986-10-07

Schain, Howard E.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Insulin; related peptides

530413, 530415, 530417, 530808, 530809, 530825, 4351723, 435240, 435241, C07K 312, C07K 318, C07K 320

Patent

active

046160787

ABSTRACT:
This specification describes a process for separating impurities from an impure mixture containing proinsulin-like material with substantially complete recovery of said proinsulin-like material, which comprises:

REFERENCES:
patent: 3649456 (1972-03-01), de Bonneville et al.
patent: 3876623 (1975-04-01), Jackson et al.
patent: 3907676 (1975-09-01), Jorgensen
patent: 4430266 (1984-02-01), Frank
Rohm and Haas Bulletin--Amberlite Polymeric Adsorbents (Undated).
Pietrzyk et al., Anal. Chem., 53, 1822-1828 (1981).
Pietrzyk et al., J. Liq. Chromatog., 5, 443-461 (1982).

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