Process for purifying phenylalanine

Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...

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210656, 435108, 562443, B01D 1508

Patent

active

050715607

ABSTRACT:
A process for the liquid phase adsorptive separation of phenylalanine from a fermentation broth containing phenylalanine salts, carbohydrates, amino acids and organic acids. The feed is contacted, at a pH of 4.5-6.5, with a hydrophobic polar, porous synthetic adsorbent, such as Amberlite XAD-7, whose functional groups have a dipole moment of 1.6-2.0, to selectively adsorb the phenylalanine onto said adsorbent to the substantial exclusion of the other feed components and recovering phenylalanine by desorbing with water, an alcohol, a ketone or an ester.

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Summary Bulletin--Amberlite Polymeric Adsorbents, Rohm & Haas (11 pages), 1978.
Preliminary Technical Notes--Amberlite.RTM. XAD-7 , Rohm & Haas (13 pages) 1978.

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