Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...
Patent
1995-06-01
1998-02-17
Smith, Lynette F.
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
4241891, 4242261, 530350, C12N 700, A61K 3929, A61K 3902, C07K 100
Patent
active
057190496
ABSTRACT:
A process is described for the purification or the hepatitis A virus, which allows one to obtain with good yields a pure product, in which organic material collected by centrifugation after lysis or the culture cells is submitted to gel filtration and successively to ion exchange chromatography.
REFERENCES:
patent: 4624918 (1986-11-01), Herschberg
patent: 4673634 (1987-06-01), Seto
patent: 4744983 (1988-05-01), Morein
patent: 5004688 (1991-04-01), Craig
patent: 5011915 (1991-04-01), Yamazaki
patent: 5151023 (1992-09-01), Kuzuhara
Flehmig, et al, 1989, "Immunogenicity of a Killed Hepatitis A Vaccine in Seronegative Volunteers" The Lancet, May 13, 1039-4041.
Welling, G.W. et al., "Isolation of Detergent-Extracted Sendai Virus Proteins by Gel-Filtration, Ion-Exchange and Reversed-Phase High-Performance Liquid Chromatography and the Effect on Immunological Activity", J. of Chrom., 1984, 297, 101-109.
Flehmig, B. et al., "Immunogenicity of a Hepatitis A Virus Vaccine", J. of Medical Virology 1987, 22, 7-16.
Locarnini, S. et al., "Purification of Hepatitis A Virus from Human Feces", Intervirology 1978, 10, 300-308.
Provost, P.J. et al., "An Inactivated Hepatitis A Viral Vaccine of Cell Culture Origin", J. of Med. Virology 1986, 19, 23-31.
Fineschi Nicoletta
Pellegrini Vittoria
Zuckerman Arie J.
Blackburn Robert P.
Chiron S.p.A.
McClung Barbara G.
Smith Lynette F.
LandOfFree
Process for purifying hepatitis A virus (HAV), virus thus purifi does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for purifying hepatitis A virus (HAV), virus thus purifi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for purifying hepatitis A virus (HAV), virus thus purifi will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1783416