Process for purifying glycopeptide phosphonate derivatives

Details Process for purifying glycopeptide phosphonate derivatives Process for purifying glycopeptide phosphonate derivatives

2007-10-25

2008-12-23

Tate, Christopher R. (Department: 1654)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Peptides containing saccharide radicals, e.g., bleomycins, etc.

C514S110000

Reexamination Certificate

active

07468420

ABSTRACT:
Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.

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