Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.
Patent
1992-02-14
1994-01-04
Griffin, Ronald W.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Glycoprotein, e.g., mucins, proteoglycans, etc.
530396, 530397, 530398, 530418, 530419, 530420, 435814, 435816, C07K 318, C07K 320, C07K 1500, C07K 1514
Patent
active
052761410
ABSTRACT:
The invention proposes a process for purifying a highly glycosylated protein from a crude preparation which comprises the action (i) of adding to said preparation a divalent metal ion in a sufficient amount in order to form a mixture which precipitates and (ii) after precipitation, of harvesting said protein from the mixture supernatant.
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Sulkowski, Eugene. "Immobilized Metal Ion Affinity Chromatography of Proteins", Protein Purification: Micro to Macro, publ. by Alan R. Liss, Inc.: New York. (1987), pp. 149-162.
Griffin Ronald W.
Transgene S.A.
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