Process for production of L-serine

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435872, C12D 1306

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active

041837860

ABSTRACT:
A process for converting glycine to L-serine is effected by the use of an aqueous medium containing glycine and microbial cells of a mutant belonging to the genus Nocardia. The mutant is capable of converting glycine to L-serine and has no or lowered ability to decompose L-serine and/or a resistance to at least one metabolic antagonist selected from those of glycine, serine, methionine, glutamine, histidine, leucine, isoleucine, valine, purine, pyrimidine or folic acid. The L-serine is accumulated in the aqueous medium and is recovered therefrom.

REFERENCES:
patent: 3843441 (1974-10-01), Kubota et al.
patent: 3871958 (1975-03-01), Nakazawa et al.
patent: 3880741 (1975-04-01), Kageyama et al.
patent: 4060455 (1977-11-01), Wagner et al.

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