Process for production of L-aspartic acid

Details Process for production of L-aspartic acid Process for production of L-aspartic acid

1995-05-19

1996-07-30

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435829, 435849, 435874, C12P 1320

Patent

active

055410901

ABSTRACT:
A process for production of L-aspartic acid comprising the steps of (1) contacting (A) an enzyme-containing material having maleate isomerase activity and aspartase activity, or (B) an enzyme-containing product having maleate isomerase activity and an enzyme-containing material having aspartase activity, with a substrate solution containing maleic acid and ammonia, and/or ammonium maleate to form L-aspartic acid, and (2) recovering L-aspartic acid from the reaction solution, characterized by adding maleic anhydride and/or maleic acid to the reaction solution to crystallize L-aspartic acid, and (3) recycling the mother liquors as the substrate solution by addition of ammonia.

REFERENCES:
patent: 3391059 (1968-07-01), Takamura et al.
patent: 4560653 (1985-12-01), Sherwin et al.
patent: 4578354 (1986-03-01), Cannon
patent: 5270190 (1993-12-01), Nakayama et al.
patent: 5338649 (1994-08-01), Inaba et al.
Chemical Abstracts, vol. 79, No. 25, pp. 357-358, Dec. 24, 1973.
Chemical Abstracts, vol. 111, No. 15, p. 819, Oct. 9, 1989.

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