Process for production of decahydroisoquinoline

Details Process for production of decahydroisoquinoline Process for production of decahydroisoquinoline

1984-12-21

1987-04-07

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21702

Patent

active

046562796

ABSTRACT:
A process for the production of decahydroisoquinoline is disclosed which comprises hydrogenating isoquinoline or partially hydrogenated isoquinoline in the presence of a ruthenium catalyst at a temperature of 110.degree. C. to 230.degree. C. under a hydrogen pressure of at least 10 kg/cm.sup.2 .multidot.G.

REFERENCES:
patent: 3205278 (1965-09-01), Lapporte
patent: 3379730 (1968-04-01), Mathison
Kimoto et al., "Chem. Pharm. Bull.", Japan, vol. 10 (1962), pp. 362-365.
Grethe, Isoquinolines, Part One, 1981, John Wiley & Sons, New York, pp. 113-114.
Bernard Witkop, "Preparation of Cis- and Trans-Decahydroisoquinolines and of Bz- Tetrahydroisoquinoline", in the Journal of the American Chemical Society, vol. 70, No. 8, Sep. 1, 1984, pp. 2617-2619.
King et al, "Synthetic and Stereochemical Investigations of Reduced Cyclic Bases, Part IV, The Constitutions of the Exhaustive Methylation Products of Trans-Octahydro-N-Methyl-Indole and of Cis- and Trans-Decahydro-N-Methylisoquinoline", in the Journal of the Chemical Society, pp. 3798-3802 (1956).

Affiliated with

Also associated with

Rating

Process for production of decahydroisoquinoline does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for production of decahydroisoquinoline, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for production of decahydroisoquinoline will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1087710