Process for production of biopterin compound

Details Process for production of biopterin compound Process for production of biopterin compound

2005-08-02

2010-10-05

Ramirez, Delia M (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

C435S252300, C435S252310, C435S254210, C435S252330, C435S227000, C435S232000, C435S190000, C435S018000, C435S025000, C435S320100, C435S325000, C530S350000, C536S023200

Reexamination Certificate

active

07807421

ABSTRACT:
The present invention provides a transformed cell which is transformed by at least one gene of enzymes participating in biosynthesis of tetrahydrobiopterin and a process for the production of a biopterin compound using the same. In accordance with the present invention, the biopterin compound can be produced in large quantities in an industrial advantageous manner from less expensive materials.

REFERENCES:
patent: 153696 (1985-09-01), None
patent: 318926 (1989-06-01), None
patent: 61-9296 (1986-01-01), None
patent: 61-52296 (1986-03-01), None
patent: 1-221380 (1989-09-01), None
patent: 4-82888 (1992-03-01), None
patent: 5-33990 (1993-05-01), None
patent: 2002-0096181 (2002-12-01), None
Branden et al., Introduction to Protein Structure, Garland Publishing Inc., New York, p. 247, 1991.
Seffernick et al., J. Bacteriol. 183(8):2405-2410, 2001.
Witkowski et al., Biochemistry 38:11643-11650, 1999.
Woo et al., Appl. Environ. Microbiol. 68(6):3138-3140, Jun. 2002.
Laufs et al., Journal of Neurochemistry 71(1):33-40, 1998.
Yamamoto et al., Metabolic Engineering 5:246-254, 2003.
Kim et al., Molecules and Cells 10(4):405-410, Aug. 31, 2000.
Weisberg et al., “Purification and Characterization of GTP Cyclohydrolase I fromDrosophila melanogaster*”, The Journal of Biological Chemistry, vol. 261, No. 3, pp. 1453-1458 (1986).
Iino et al., “Discovery of a new tetrahydrobiopterin-synthesizing enzyme in thelemonmutant of the silkwormBombyx mori” Biochimica et Biophysica Acta, vol. 1297, pp. 191-199 (1996).
Maier et al., “Biosynthesis of Pteridines inNeurospora crassa, Phycomyces blakesleeanusandEuglena gracilis:: Detection and Characterization of Biosynthetic Enzymes*”,Photochemistry and Photobiology, vol. 61, No. 1, pp. 43-53.
Son et al., “Cyclic Guanosine -3′,5′-Monophosphate and Biopteridine Biosynthesis inNocardiasp.”,Journal of Bacteriology, vol. 182, No. 13, pp. 3644-3648 (2000).
Wede et al., “Neopterin Derivatives Modulate Toxicity of Reactive Species onEscherichia coli”, Free Radic. Res., vol. 31, No. 5, pp. 381-388 (1999).
Ishi et al., “Improved Inosine Production and Derepression of Purine Nucleotide Biosynthetic Enzymes in 8-Azaguanine Resistant Mutants ofBacillus subtilis”, Agr. Biol. Chem., vol. 36, No. 9, pp. 1511-1522 (1972).
Matsui et al., “Production of Guanosine by Psicofuranine and Decoyinine Resistant Mutants ofBacillus subtilis” Agr. Biol. Chem., vol. 43, No. 8, pp. 1739-1744 (1979).
Tiedeman et al., “Nucleotide Sequence of theguaA Gene Encoding GMP Synthetase ofEscherichia coilK12*”,The Journal of Biological Chemistry, vol. 260, No. 15, pp. 8676-8679 (1985).
Stragier et al., “Processing of a Sporulation Sigma Factor inBacillus subtilis: How Morphological Structure Could Control Gene Expression”,Cell, vol. 52, pp. 697-704 (1988).
Takikawa et al., “Biosynthesis of Tetrahydrobiopterin”Eur. J. Biochem, vol. 161, pp. 295-302 (1986).
Katzenmeier et al., “Biosynthesis of Tetrahydrofolate”,Biol. Chem. Hoppe-Seyler, vol. 372, pp. 991-997 (1991).
Inoue et al., “Purification and cDNA Cloning of Rat 6-Pyruvoyl-tetrahydropterin Synthase*”,The Journal of Biological Chemistry, vol. 266, No. 31, pp. 20791-20796 (1991).
Yanisch-Perron et al., “Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors”Gene, vol. 33, pp. 103-119 (1985).
Citron et al., “Isolation and expression of rat liver sepiapterin reductase cDNA”,Proc. Natl. Acad. Sci. USA, vol. 87, pp. 6436-6440 (1990).
Tettelin et al., “The nucleotide sequence ofSaccharomyces cerevisiaechromosome VII”,Nature, vol. 387, pp. 81-84 (1997).
Miller, “Nitrosoguanidine Mutagenesis”,Experiments in Molecular Genetics, Experiment 14, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, pp. 125-129 (1972).
N. Schramek et al., “Functional expression of murine phenylalanine hydroxylase inEscherichia coli”, Corresponding Chemical Abstract: Proceedings of the International Symposium on Pteridines and Folates, 11thBerchtesgaden, Germany, Jun. 15-20, pp. 527-530, (1997) CAN 128:304545 AN 1998:224650.
Broun et al.,Science, vol. 282, pp. 1315-1317 (1998).
Van de Loo et al.,Proc. Natl. Acad. Sci., vol. 92, pp. 6743-6747 (1995).
Seffernick et al.,J. Bacteriol., vol. 183, No. 8, pp. 2405-2410 (2001).
Witkowski et al.,Biochemistry, vol. 38, pp. 11643-11650 (1999).
Y. Miwa et al., “Possible function and some properties of the CcpA protein ofBacillus subtilis”, Microbiology, vol. 140, pp. 2567-2575 (1994).
Laufs et al.,Journal of Neurochemistry, vol. 71, No. 1, pp. 33-40 (1998).
Watanabe et al.Seikagaku, vol. 53, No. 8, p. 1008 (1981), with English translation.
Oettl et al., “Formation of Oxygen Radicals in solutions of 7,8-Dihydroneopterin”,Biochemical and Biophysical Research Communications, vol. 264, pp. 262-267 (1999).
Tiedeman et al., “Nucleotide Sequence of theguaB locus Encoding IMP dehydrogenase ofEscherichia coliK12*”,Nucleic Acid Research, vol. 13, No. 4, pp. 1303-1316 (1985).
Gollinick et al., “Themtrlocus is a two-gene operon required for transcription attenuation in thetrpoperon ofBacillus subtilis”, PNAS USA, vol. 87, pp. 8726-8730 (1990).
B. Thöny et al., “Tetrahydrobiopterin biosynthesis, regeneration and functions”,Biochem. J., vol. 347, pp. 1-16, 2000.

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