Process for production of avermectin aglycones and cultures ther

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435 76, 4352535, 4351721, 4351722, 435244, 536 71, C12P 1718, C12N 120

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055762000

ABSTRACT:
Mutants of Streptomyces avermitilis lacking ability to produce glycosylated avermectins and lacking branched-chain 2-oxo acid dehydrogenase activity, method for preparation thereof, and use thereof to produce natural and non-natural avermectin aglycones useful as parasiticides.

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