Process for production of antibiotic U-64,767 using Streptomyces

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435253, 435886, C12P 1706, C12N 120, C12R 1465

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active

043979505

ABSTRACT:
Novel antibiotic U-64,767 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces macronensis Dietz sp.n., NRRL 12566. This antibiotic is active against various Gram-positive bacteria, for example, Staphylococcus aureus and Streptococcus pyogenes. It is also active against the Gram-negative bacterium Streptococcus pneumoniae. Thus, antibiotic U-64,767 can be used in various environments to eradicate or control such bacteria.

REFERENCES:
patent: 3515717 (1970-06-01), Cha et al.
Bognar et al., Acta. Chim. Acad. Sci. Hung., 56, 53-60, 1968.

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