Process for production of an antibiotic compound with Zalerion a

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide

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435 711, 435911, 4352541, C12P 2100

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active

054260388

ABSTRACT:
A process for producing an antibiotic compound which is normally a minor component in the cultivation of Z. arboricola to be the major product is described.

REFERENCES:
patent: 4931352 (1990-06-01), Fromtling
D. A. Hopwood, "The Isolation of Mutants" Ch. VII, pp. 363-433, Methods in Microbiology, vol. 3A, Academic Press, 1970.
C. T. Calam, "Improvement of Microorganisms by Mutation, Hydridization & Selection" Ch. VII, pp. 435-549, Methods in Microbiology, vol. 3A, Academic Press, 1970.
R. E. Schwartz, et al., J. Antibiotics 42, 163-167 (1989).
C. F. Wichmann, et al., J. Antibiotics 42, 168-173 (1989).

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