Process for production of 2-substituted-4-hydromethylimidazole c

Details Process for production of 2-substituted-4-hydromethylimidazole c Process for production of 2-substituted-4-hydromethylimidazole c

1992-09-03

1993-11-30

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D23360, C07D23354

Patent

active

052667049

ABSTRACT:
The invention provides a process for producing a 2-substituted-4-hydroxymethylimidazole easily and in good yield by means of simple equipment. This process comprises reacting hydroxymethylglyoxal, a monoaldehyde and ammonia in a sequence such that said monoaldehyde and ammonia are first reacted with each other and hydroxymethylglyoxal is then introduced into the reaction system for further reaction.

REFERENCES:
patent: 4074054 (1978-02-01), Christidis et al.
patent: 4107308 (1978-08-01), Paul et al.
patent: 4567276 (1986-01-01), Baldwin
patent: 4719309 (1988-01-01), Mesch et al.
patent: 4851526 (1989-07-01), Greenberg et al.
patent: 4853383 (1989-08-01), Baldwin et al.
Hofmann, K., Imidazole and its Derivatives, Part I, New York, pp. 33-38 (1953).

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