Process for production of 1-aryloxy-aminopropane derivatives

Details Process for production of 1-aryloxy-aminopropane derivatives Process for production of 1-aryloxy-aminopropane derivatives

1978-06-06

1982-11-23

Hines, Robert V.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549366, C07D20724, C07D31706

Patent

active

043604641

ABSTRACT:
A process for the preparation of 1-aryloxy-3-aminopropane derivatives and acid addition salts thereof and such products per se the process comprising ring opening of tertiary azetidinol derivatives. They possess .beta.-adrenergic blocking activity and an activity of controlling secretion of gastric juice and are therefore useful antiulcerative medicines for peptic ulcer and duodenal ulcer.

REFERENCES:
patent: 3415873 (1968-12-01), Stevens
patent: 3432545 (1969-03-01), Howe
patent: 3501769 (1970-03-01), Crowther et al.
patent: 3551493 (1970-12-01), Ruschig et al.
Gaertner, "Journal of Heterocyclic Chemistry", vol. 6, No. 3, pp. 273-277, (1969).

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