Process for producing vitamin B6

Details Process for producing vitamin B6 Process for producing vitamin B6

2008-05-13

2008-05-13

Saidha, Tekchand (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

C435S041000, C435S183000, C435S189000, C435S252300, C435S320100, C530S350000, C536S023200

Reexamination Certificate

active

07371547

ABSTRACT:
Disclosed is a mutant of a recombinant microorganism of the genusSinorhizobiumcapable of producing vitamin B6having a recombinant plasmid with pdxJ gene that acquired histidine requirement of glycine resistance, or its combination thereof.

REFERENCES:
patent: 0 765 938 (1997-04-01), None
patent: 0 950 715 (1999-10-01), None
Laber et al. FEBS Lett. 1999 Apr. 16;449(1):45-8.
Tazoe, M. et al., “Production of Vitamin B6in Rhizobium, ”Biosci. Biotechnol. Biochem., vol. 63, No. 8, pp. 1378-1382 (1999).
Tazoe, M. et al., “Biosynthesis of Vitamin B6in Rhizobium,”J. Biol. Chem., vol. 275, No. 15, pp. 11300-11305 (2000).
Laber, B. et al., “Vitamin B6biosynthesis: formation of pyridoxine 5'-phosphate from 4-(phosphohydroxy)-L-threonine and Ideoxy-D-xylulose-5-phosphate by PdxA and PdxJ Protein,”FEBS Letters, vol. 449, pp. 45-48 (1999).
Tazoe, M. et al., “Biosynthesis of Vitamin B6in Rhizobium: In Vitro Synthesis of Pyridoxine 1-Deoxy-D-xylulose and 4-Hydroxy-L-threonine,”Biosci. Biotechnol. Biochem, vol. 66, No. 4, pp. 934-936 (2002).
Capela, D. et al., “Analysis of the Chromosome Sequence of the Legume Symbiont Sinorhizobium meliloti Strain 1021.”Proc. Natl. Acad. Sci., vol. 98, No. 17, pp. 9877-9882 (2001).
Galibert, F. et al., “The Composite Genome of the Legume Symbiont Sinorhizobium meliloti,”Science, vol. 293, pp. 668-672 (2001).
Mittenhuber, G., “Phylogenetic Analyses and Comparative Genomics of Vitamin B6(Pyridoxine) and Pyridoxal Phosphate Biosynthesis Pathways,”J. Mol. Microbiol. Biotechnol., vol. 3, No. 1, pp. 1-20 (2001).
Capela, D. et al., “Analysis of the Chromosome sequence of the legume symbiont Sinorhizobium meliloti Strain 1021,”Proc. Natl. Acad. Sci, vol. 98, No. 17, pp. 9877-9882 (2001), NCBI Database Abstract No. XP-002272564.
Galibert, F. et al., “The Composite Genome of the Legume Symbiont Sinorhizobium meliloti,”Science, vol. 293, pp. 668-672 (2001), NCBI Database Abstract No. XP-002272565.

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