Process for producing triazine compounds

Details Process for producing triazine compounds Process for producing triazine compounds

1992-04-14

1993-10-05

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D25118

Patent

active

052506860

ABSTRACT:
A process for producing a triazine derivative of the formula (III), ##STR1## wherein R.sup.1 is a C.sub.1 -C.sub.4 alkyl group, n is an integer of O to 2, R.sup.2 is hydrogen or a C.sub.1 -C.sub.2 alkyl group, and X is a halogen atom,
which comprises reacting a biguanide derivative of the formula, ##STR2## wherein R.sup.1 and n are as defined in the formula (III), and X' is a halogen atom,
with a halocarboxylic acid ester of the formula, ##STR3## wherein R.sup.2 and X are as defined in the formula (III), and R.sup.3 is a C.sub.1 -C.sub.4 alkyl group,
in the presence of a base, wherein a dehydrating agent is present in the reaction system, and processes for producing 2-fluoroisobutyric acid ester as an intermediate compound for the production of the triazine derivative.

REFERENCES:
patent: 2926165 (1960-02-01), Shapiro et al.
patent: 3767656 (1973-10-01), Diamond et al.
patent: 3816419 (1974-06-01), Cross et al.
Purrington et al., "Preparation of .alpha.-Fluoro Carboxylic Acids and Derivatives", J. Org. Chem., 1990, 55, 3423-3424.
Gensler et al., "Fluorination of Methyl Isobutyrate with Perchloryl Fluoride", J. Org. Chem., vol. 33, No. 11, 1968, Notes 4279-4281.
E. M. Smolin et al., "s-Triazines and Derivatives", (The Chemistry of Heterocyclic Compounds), Jun. 1967, pp. 226-229, Interscience Publishers Inc., New York US.

Affiliated with

Also associated with

Rating

Process for producing triazine compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for producing triazine compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing triazine compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1005347