Process for producing thymosin

Details Process for producing thymosin Process for producing thymosin

1977-06-23

1978-12-05

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424177, 2601125R, 260112R, A61K 3526, A61K 3556, A61K 3724

Patent

active

041286375

ABSTRACT:
Thymosin is produced by an improved process in which thymus glands are coarse ground, extracted in saline solution which is filtered and the filtrate or extract is injected with steam for a brief period of time to denature undesired proteins without denaturing the thymosin, whereby a precipitate is formed which is separated by filtration. The filtrate is concentrated and cooled and crude thymosin is precipitated by adding the concentrate to acetone.

REFERENCES:
patent: 3657417 (1972-04-01), Brunetti et al.
patent: 4010148 (1977-03-01), Goldstein

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