Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide
Patent
1991-02-28
1994-02-15
Marx, Irene
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using a micro-organism to make a protein or polypeptide
4352535, 4352521, 435886, 435170, 435822, C12P 2104, C12N 120
Patent
active
052866319
ABSTRACT:
Newly-discovered antibiotic A10255 factors B, C, E, and F are produced by submerged aerobic fermentation of previously-unknown Streptomyces gardneri strain NRRL 15922, or an A10255-producing variant, mutant or recombinant thereof. The antibiotics are active against a wide variety of pathogenic bacteria, and also enhance feed-utilization efficiency in chickens, weanling pigs and cattle.
REFERENCES:
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patent: 3689639 (1972-09-01), Bergy et al.
J. M. Liesch and K. L. Rinehart, "Berninamycin 3. Total Structure of Berninamycin A", J. Amer. Chem. Soc. 99 (5), 1645-1646 (1977).
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Gardner et al., Br. J. Exp. Pathol. 23, 123 (1942).
Index of Antibiotics from Actinomyces, H, Umezawa, Ed., University of Tokyo Press, vol. I, p. 533 (1967).
Chem. Abstr. 79 (25): 144 870n (1973), abstracting JP-B-7300,075 (Kyowa Fermentation Industry).
Chem. Abstr. 68 (25): 112 328y (1968), abstracting M. A. Laneelle et al., Ann Inst. Pasteur 114 (3), 305-312 (1968).
Bergey's Manual of Determinative Bacteriology, 9th Ed., 194, pp. 748-750.
CRC Handbook of Microbiology, vol. III, 1973, p. 825.
R. Suhadolnik in Vanek et al., Genetics of Industrial Microorganisms, vol. II, 1973, pp. 335-338.
ATCC Catalog of Bacteria, 1989, p. 236.
Boeck LaVerne D.
Godfrey, Jr. Otis W.
Michel Karl H.
Eli Lilly and Company
Fontana Steven A.
Marx Irene
Whitaker Leroy
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