Process for producing taurine analogues

Details Process for producing taurine analogues Process for producing taurine analogues

1996-08-14

1997-10-21

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Sulfinic or sulfenic acids or salts thereof

C07C31302

Patent

active

056798458

ABSTRACT:
The present invention relates to a process for producing amino/guanidinothiosulfonic acid, which comprises treating a styrenedivinylbenzene copolymer sulfonate of amino/guanidinoethyl disulfoxide into contact with an alkali, selectively eluting amino/guanidinosulfinic acid, then reacting this product in a non-aqueous solvent in the presence of a base, and passing the reaction product through a weakly acidic cation exchange resin column; in accordance with the present invention, hypotaurine, thiotaurine and the like having a high purity can industrially be produced.

REFERENCES:
patent: 2212783 (1940-08-01), Lavine
Chemical Abstracts, vol. 70, No. 9, 12 May 1969, Columbus, Ohio, Abstract no. 88237.
W. Mansfield Clark et al., "Biochemical Preparations", Biochemical Preparations, Inc., 10(72-75, 1963.
CA 83:53205 J Med Chem (1975) 18(5) 502-5 "Probiotics etc" Fujii.
CA 78:15513--SU 350787 Sep. 13, 1972 Hypotaurine Pustoshkin.
CA 95:149880 J. Labelled Compd Radiopharm (1981) 18(5) 765-8 Fellman sythesis-etc.

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