Process for producing suppositories by compression and supposito

Details Process for producing suppositories by compression and supposito Process for producing suppositories by compression and supposito

1995-05-26

1997-05-13

Bawa, Raj

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424DIG15, 514966, 514967, 514968, A61K 902

Patent

active

056290128

ABSTRACT:
Suppositories, produced by a process in which a suppository basic mass is produced containing (a) 50-75% of 5-aminosalicylic acid as an active ingredient, (b) 2-5% talc, magnesium stearate and/or polyvinyl pyrrolidone and (c) 20-48% by weight of a polyethylene glycol having an average molecular weight of at least 4000, and the produced mass is compressed to suppositories in a tabletting machine.

REFERENCES:
patent: 3849549 (1974-11-01), Dempski et al.
Gennaro, A. R. (1985). Remington's Pharmaceutical Sciences. Mack Pub. Co., pp. 1580-1584.

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