Process for producing sugar chains using...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

Reexamination Certificate

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C530S350000, C536S023200

Reexamination Certificate

active

10363145

ABSTRACT:
The present invention provides a novel polypeptide having a β1,3-N-acetylglucosaminyltransferase activity, an agent for synthesizing a sugar chain comprising the polypeptide, a process for producing a sugar chain or a complex carbohydrate using the agent for synthesizing a sugar chain, DNA encoding the polypeptide, a process for producing the polypeptide, an antibody against the polypeptide, and a diagnosis method and a medicament for treatment for inflammation, cancer or tumor metastasis using the DNA or the antibody. The present invention is useful for synthesis of a useful sugar chain and diagnosis and treatment for inflammatory diseases, cancer or tumor metastasis.

REFERENCES:
patent: WO 01/44479 (2001-06-01), None
patent: WO 02/04612 (2002-01-01), None
patent: WO 02/18556 (2002-03-01), None
Zhou et al. Accession AAD09763. Aug. 9, 2000.
Zhou et al. Proc Natl Acad Sci U S A. Jan. 19, 1999;96(2):406-11.
Sato, et al.,Proc. Natl. Acad. Sci., vol. 95 (1998), pp. 472-477.

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