Process for producing sugar chain asparagine derivative

Details Process for producing sugar chain asparagine derivative Process for producing sugar chain asparagine derivative

2011-06-07

2011-06-07

Ariani, Kade (Department: 1651)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

C435S068100, C435S085000, C435S091530, C435S101000, C536S001110, C536S017200, C536S127000

Reexamination Certificate

active

07955819

ABSTRACT:
A process for preparing asparagine-linked oligosaccharide derivatives including the steps of: (a) treating a delipidated egg yolk with a protease to obtain a mixture of peptide-linked oligosaccharides, (b) treating the mixture of peptide-linked oligosaccharides with a peptidase to obtain a mixture of asparagine-linked oligosaccharides, (c) introducing a lipophilic protective group into the asparagine-linked oligosaccharides in the mixture to obtain a mixture of asparagine-linked oligosaccharide derivatives, and (d) subjecting the mixture of asparagine-linked oligosaccharide derivatives to chromatography to separate the mixture into individual asparagine-linked oligosaccharide derivatives.

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