Process for producing steroidal 7.alpha.-acylthio-4-en-3-ones

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07J 1900

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042139023

ABSTRACT:
A steroidal 7.alpha.-acylthio-4-en-3-one is produced by adding a thiocarboxylic acid to a steroidal 4,6-dien-3-one in the presence of a strong acid in a neutral organic solvent.

REFERENCES:
patent: 3894006 (1975-07-01), Stache et al.
patent: 4118488 (1978-10-01), Philippson et al.
Schaub et al., J. Org. Chem. 26 (1961), pp. 3915-3925.

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