Process for producing staurosporine derivatives

Details Process for producing staurosporine derivatives Process for producing staurosporine derivatives

1993-06-22

1994-09-06

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540546, C07D49822

Patent

active

053449266

ABSTRACT:
Disclosed is a process for producing a staurosporine derivative represented by Formula (I): Q is defined as in specification: ##STR1## The staurosporine derivative (I-1) possesses selective protein kinase C-inhibitory and cell growth-inhibiting activities, and platelet-increasing activity.

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patent: 5015578 (1991-05-01), Schroeder et al.
Takahashi et al. J. Antibiotics, Dec. 1987, pp. 1782-1784.
Journal of Antibiotics, 42, 564 (1989).
Journal of Antibiotics, vol. 42, No. 4, 1989, pp. 571-576, I. Takahashi et al., "UCN-01 and UCN-02, New Selective Inhibitors of Protein Kinase C. II. Purification,, Physico-Chemical Properties, Structural Determination and Biological Activities".

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