Process for producing stable solutions of a sulphonamide and a p

Details Process for producing stable solutions of a sulphonamide and a p Process for producing stable solutions of a sulphonamide and a p

1977-01-31

1979-01-09

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

424251, A61K 31625, A61K 31505

Patent

active

041338790

ABSTRACT:
A process for the production of limpid and stable injectable preparations containing a sulphonamide and a potentiator is described, in which a diethanolamine salt of the sulphonamide and a salt of the potentiator are separately dissolved and the solutions mixed, the solvent mixture containing between 10 and 50% of water, between 15 and 30% of propyleneglycol, and between 20 and 40% of N-methylpyrrolidone, and the pH of the preparation being from 5.5 to 7.5.

REFERENCES:
patent: 3551564 (1970-12-01), Klaui et al.
patent: 3985876 (1976-10-01), Hazlett et al.
patent: 4031214 (1977-06-01), Easterbrook
patent: 4041160 (1977-08-01), Stolar

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