Process for producing stable pharmaceutical forms of an ergoline

Details Process for producing stable pharmaceutical forms of an ergoline Process for producing stable pharmaceutical forms of an ergoline

1993-08-09

1996-06-04

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

Ophthalmic preparation

424422, A61K 338, A61K 908

Patent

active

055230822

ABSTRACT:
The invention relates to new pharmaceutical compositions intended for administration by ocular route and to the process for obtaining them.
A specific subject of the invention is a process for obtaining pharmaceutical compositions intended for ophthalmic route of which the active ingredient is bromocriptine, in which the active ingredient is dissolved in methanol then this solution is diluted with an aqueous solute containing a hydrosoluble inert filler, the mixture is lyophilized then the lyophilization deposit is redissolved at the time of use in an aqueous solute containing a preservative, a polyethylene glycol, physiological serum and an ethylenic acid.
The solute obtained is a medicament for intra-ocular hypertension.

REFERENCES:
patent: 4657925 (1987-04-01), Horn

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