Process for producing stable macromomycin powder

Details Process for producing stable macromomycin powder Process for producing stable macromomycin powder

1977-06-01

1978-07-25

Meyers, Albert T.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Processes of making, purifying or recovering

424117, A61K 3500

Patent

active

041029992

ABSTRACT:
There is provided a process for producing a stable macromomycin (hereinafter often referred to as MCR) powder which comprises adding a stablilizer selected from the group consisting of saccharides, amino acids and salts thereof, organic acid salts, inorganic acid salts and a chelating agent to a solution of macromomycin purified from fermentation broth prior to dehydration as by lyophilization.

REFERENCES:
patent: 3595954 (1971-07-01), Umezawa et al.
Chimura et al., Journal of Antibiotics, vol. 21, No. 1, Jan. 1968, pp. 44-49.
Yamashita et al., Journal of Antibiotics, 29 (4), Apr. 1976, pp. 415-423.

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