Process for producing slippery, tenaciously adhering hydrogel co

Details Process for producing slippery, tenaciously adhering hydrogel co Process for producing slippery, tenaciously adhering hydrogel co

1995-02-01

1997-09-02

Dudash, Diana

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Flexible web, sheet, film, or filament base

427 228, 427301, 427318, 427322, 427534, 427536, B05D 310, B05D 304, C23C 1402

Patent

active

056629605

ABSTRACT:
A process for preparing coating compositions of a commingled hydrogel of a polyurethane-polyurea polymer hydrogel and a poly(N-vinylpyrrolidone) polymer hydrogel; a process for making materials composed of a polymeric plastic or rubber substrate or a metallic substrate, with a coating of the commingled hydrogel thereon; and a process for making medical devices with a coating of the commingled hydrogel thereon, are disclosed. The coating compositions tenaciously adhere to the substrate materials and medical devices to which they are applied due to bonding of a tie coat to a reactive substrate surface and due to the commingling of the two hydrogel components. The coating compositions and coated materials and medical devices are non-toxic and biocompatible, making them ideally suited for use in applications such as for catheters, catheter balloons and stents. In such applications, the coating compositions, coated materials, and coated medical devices made therefrom demonstrate low coefficients of friction in contact with body fluids, especially blood, as well as a high degree of wear permanence over prolonged use. The commingled hydrogel coatings are capable of being dried to facilitate storage of the devices to which they have been applied, and can be instantly reactivated for later use by exposure to water.

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