Process for producing S-adenosyl-L-homocysteine

Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Resolution of optical isomers or purification of organic...

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435 84, 435 85, 435 88, 435113, 435118, 435119, 435193, 435829, 435874, 435877, 435929, 435940, C07P 4100, C12P 1926, C12P 1928, C12P 1940

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046056254

ABSTRACT:
S-adenosyl-L-homocysteine is produced by contacting adenosine with D-homocysteine in an aqueous medium in the presence of cells or treated cells of a microorganism of the genus Pseudomonas having the ability to racemize D-homocysteine to DL-homocysteine and in the presence of S-adenosyl-L-homocysteine hydrolase, to synthesize S-adenosyl-L-homocysteine, and thereafter collecting it.

REFERENCES:
patent: 4080259 (1978-03-01), Boesten et al.
Chemical Abstract I: 98: 194538y (1983) Prep. Biochem., 12(5) 395-415.

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