Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound other than saccharide containing...
Patent
1992-09-09
1994-08-02
Lilling, Herbert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound other than saccharide containing...
4352525, C12P 2500, C12N 120
Patent
active
053345100
ABSTRACT:
The present invention provides a process for producing riboflavin by fermentation, a method for providing microorganisms having an improved riboflavin-producing capability, and strains of microorganisms having improved riboflavin-producing ability. The strains of the present invention belong to the genus Bacillus, have reduced activity of hydrolysing phosphoric acid from 5'-guanylic acid, and have the ability of producing riboflavin. Mutants used in the processes of this invention have an improved ability of producing riboflavin and are capable of producing or accumulating a large amount of riboflavin in the culture medium. The processes of this invention are therefore suitable for producing riboflavin in an effective manner at a low cost.
REFERENCES:
patent: 3900368 (1975-09-01), Enei et al.
patent: 4165250 (1979-08-01), Epstein et al.
Matusi et al Agric Biol Chem 46(8) p. 2003-2008 1982 Riboflavin Production By Roseoflavin-resistant . . . .
Nakamatu Tuyoshi
Usui Naoki
Yamamoto Yoko
Ajinomoto Co. Inc.
Lilling Herbert J.
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