Process for producing riboflavin

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound other than saccharide containing...

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4351723, 4353201, 4352523, 43525232, 43525233, 536 232, C12P 2500, C12N 121, C12N 1552, C12N 1563

Patent

active

055893554

ABSTRACT:
The present invention provides a process for producing riboflavin efficiently at a low cost, wherein riboflavin is formed and accumulated in a medium by culturing a microorganism carrying a recombinant DNA prepared by inserting into a vector DNA a DNA which is derived from a microorganism belonging to the genus Corynebacterium or Brevibacterium and which, upon introduction into a riboflavin-requiring microorganism, confers on the microorganism the ability to complement its riboflavin requirement.

REFERENCES:
patent: 4500640 (1985-02-01), Katsumata et al.
patent: 4617267 (1986-10-01), Katsumata et al.
patent: 4710471 (1987-12-01), Katsumata et al.
patent: 5164303 (1992-11-01), Heefner et al.
Clarke et al., (1979) Methods in Enzymology 68:396-408.
Ayala et al., (1980) Modern Genetics, Benjamin/Cummings Publishing Company, Inc. (Menlo Park, CA) pp. 151-154.

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