Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1984-04-13
1985-11-12
Shapiro, Lionel M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435872, C12P 1960, C12R 1365
Patent
active
045528420
ABSTRACT:
A novel antitumor agent designated herein as rebeccamycin is produced by fermentation of Nocardia aerocolonigenes (ATCC 39243). Rebeccamycin and its 5'-N-methyl and 5',2",3",6"-tetraacetate derivatives exhibit activity against experimental animal tumor systems.
REFERENCES:
J.C.S. Chem. Comm., pp. 800-801, (1978), Furusaki et al.
J. Antibiotics 30(4): 275-282, (1977), Omura et al.
Angew. Chem. Int. Engl. 19(6): 459-460, (1980), Steglich et al.
Bradner William T.
Bush James A.
Doyle Terrence W.
Nettleton, Jr. Donald E.
Bristol-Myers Company
Morse David M.
Shapiro Lionel M.
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