Process for producing pyrrolidine derivative

Details Process for producing pyrrolidine derivative Process for producing pyrrolidine derivative

2004-05-07

2008-03-18

Saeed, Kamal A. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07345179

ABSTRACT:
This invention provides an industrially useful process for producing 1,4-transcyclohexanecarboxylic acid derivative (1) which has excellent VLA-4 inhibitory action and safety, and an intermediate which is useful in such method. More particularly, this invention relates to a process for converting a compound of formula (I) into a compound of formula (VI) by the reaction scheme:

REFERENCES:
patent: 7157487 (2007-01-01), Nakayama et al.
patent: 61-251635 (1986-11-01), None
patent: 06-306025 (1994-11-01), None
patent: 2001/00206 (2001-01-01), None
patent: 02/053534 (2002-07-01), None
U.S. Appl. No. 10/584,240, filed Jun. 26, 2006, Nakayama et al.
U.S. Appl. No. 10/556,043, file Nov. 8, 2005, Nakayama et al.
U.S. Appl. No. 10/584,141, filed Jun. 26, 2006, Takayanagi et al.

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