Process for producing pyridine compound

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

Reexamination Certificate

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Reexamination Certificate

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10486037

ABSTRACT:
The present invention provides a process for producing the pyridine compound [d]:[wherein R3and R4are as defined below],which has an excellent herbicidal activity, by making a pyridine compound [a]:[wherein R1represents a C1–C6 alkoxy group, R3represents a halogen atom, cyano group or nitro group, and R4represents a hydrogen atom or halogen atom] react with an α-diazoester compound [f]:in-line-formulae description="In-line Formulae" end="lead"?N2CHCOR1[f]in-line-formulae description="In-line Formulae" end="tail"?[wherein R1is defined above]in the presence of an acid.

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Nishiyama, H., et al., “Reaction of Some Amides and Thioamides with Diazomethane Catalyzed by Silica Gel”,Tetrahedron Letters, No. 48, pp. 4671-4674 (1979).
Busch-Petersen, J., et al., “A Rhodium (II) Catalytic Approach to the Synthesis of Ethers of a Minor Component in a Tautomeric Set”,Organic Letters, vol. 2, No. 11, pp. 1641-1643 (2000).
M.P. Cava, “Pyridine Derivatives, II”,Journal of Organic Chemistry, vol. 23, No. 11, (1958).

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