Process for producing pure form of...

Details Process for producing pure form of... Process for producing pure form of...

2004-07-14

2011-10-25

Coleman, Brenda (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

active

08044196

ABSTRACT:
Disclosed is a process for producing pure form of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine. The process comprises of reacting 2-(2-aminoanilino)-5-methylthiophene-3-carbonitrile with N-methyl piperazine in conjunction with N-methylpiperazine acid salt, to produce 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine. Also disclosed is a process for obtaining the Polymorphic Form I of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine by crystallizing the crude 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine in a mixture of solvents.

REFERENCES:
patent: 7425627 (2008-09-01), Dolitzky et al.
patent: 7759484 (2010-07-01), Dalmases Barjoan et al.

Affiliated with

Also associated with

Rating

Process for producing pure form of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for producing pure form of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing pure form of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4287187