Process for producing optically active epoxy alcohol derivatives

Details Process for producing optically active epoxy alcohol derivatives Process for producing optically active epoxy alcohol derivatives

1993-01-29

1993-10-12

Evans, Joseph E.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549513, 549556, C07D30100, C07D30132, C07D30308, C07D30316

Patent

active

052527590

ABSTRACT:
Organic sulfonate derivatives of optically active epoxy alcohols such as (R)- or (S)- glycidol are conveniently prepared from aqueous solutions of the epoxy alcohols.

REFERENCES:
patent: 2755290 (1956-07-01), Mueller
patent: 4346042 (1982-08-01), Baldwin et al.
patent: 4877892 (1989-10-01), Brittelli
patent: 4946974 (1990-08-01), Sharpless et al.
patent: 5084582 (1992-01-01), Genet et al.
patent: 5136062 (1992-08-01), Millar et al.
patent: 5145974 (1992-09-01), Paul et al.
patent: 5153338 (1992-10-01), Sharpless et al.
Mesnard et al., "Effect of Tosyl Chloride on Monohydric Alcohols", C. R. Acad. Sci., Nov. 13, 1963, pp. 2999-3001.
Klunder et al., "Arenesol Fonate Derivatives of Homochiral Glycidol: Versatile Chiral Building Blocks For Organic Synthesis", J. Org. Chem. 54, pp. 1295-1304 (1989).
Gao et al., "Catalytic Asymmetric Expoxidation and Kinetic Resolution: Modified Procedures Including in Situ Derivatization", J. Am. Chem. Soc. 109, pp. 5765-5780 (1987).
Klunder et al., "Asymmetric Epoxidation of Allyl Alcohol: Efficient Routes to Homochiral B-Adrenergic Blocking Agents", J. Org. Chem. 51, pp. 3710-3712 (1986).
Baldwin et al., "Synthesis of (R)- and (S)-Epichlorohydrin", J. Org. Chem. 43, pp. 4876-4878 (1978).
Chautemps et al., "Preparation de Sulfonates d'Alcools Ethyleniques et d'Epoxyalcools", C. R. Acad. Sci. Ser. C., Feb. 26, 1968, pp. 622-644.
Nakabayashi et al., "Some Reactions of the Glycidyl Esters of Sulfonic Acids", Bull. Chem. Soc. Japan 39, pp. 413-417 (1966).
Szeija, "Synthesis of Sulfonic Esters Under Phase-Transfer Catalysed Conditions", Synthesis, Oct. 1979, pp. 822-823.
Czech. 148,516 (Abstract only); Chem. Abstract 79: 115310z)(1973).

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