Process for producing optically active compounds having pyridine

Details Process for producing optically active compounds having pyridine Process for producing optically active compounds having pyridine

1988-08-02

1990-11-20

Rosen, Sam

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435122, C12P 1712

Patent

active

049719092

ABSTRACT:
The present invention provides a process for producing optically active compounds by a biochemical method in which specific compounds having pyridine skeletons and hydroxyl groups are reacted with esters in the presence of hydrolases.
The compounds have the following general formula: ##STR1## wherein X is selected from substituted pyridyl groups. Y is selected from hydrogen and halogen atoms, a cyano group, and a trifluoromethyl group. R is an alkylene group having 1-20 carbon atoms, and n is 0 or 1. Q is an alkylene group having 1-20 carbon atoms and m is 0 or 1.

REFERENCES:
patent: 4568641 (1986-02-01), Bewick
Zaks et al., Chem. Abst., vol. 103 (1985), p. 2819t.

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