Process for producing optically active aminopolycarboxylic acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435109, 435232, 562565, C12P 1320

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active

059812389

ABSTRACT:
A process for producing an optically active aminopolycarboxylic acid, such as S,S-ethylenediamine-N,N'-disuccinic acid, from a mixture of a diamine, such as ethylenediamine, with fumaric acid using a microorganism having a lyase activity, wherein at least one metal ion selected from the group consisting of an alkaline earth metal, iron, zinc, copper, nickel, aluminum, titanium and manganese is added to the reaction system. According to this process, aminopolycarboxylic acids, such as S,S-ethylenediamine-N,N'-disuccinic acid, or metal complexes thereof, can be appropriately and efficiently produced while improving the reaction yield.

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Nishikiori, Takaaki et al., "Production by Actinomycetes of (S,S,), N,N'-ethylendiaminedisuccinic acid, an inhibitor of phospholipase C", J. Antibiot, (1984).

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